Born 29 March, 1923 in Abeokuta, Nigeria Prof. Lambo had his early education in Abeokuta before he proceeded to the University of Birmingham, England where he qualified as a medical doctor, and the Institute of Psychiatry University of London, where he graduated as specialist Psychiatrist. Prior to his appointment with WHO, he held many distinguished positions where he was instrumental to the development of medical services in Nigeria. He returned to Nigeria in 1951, served as a medical officer in many hospitals before he became the specialist in-charge of a hospital for nervous diseases at Abeokuta popularly called Aro (Psychiatry) hospital. He was consultant physician at the University College Hospital Ibadan, headed the Department of Psychiatry at the institution, he rose to the post of Vice-chancellor of the University (1968-71). Thereafter, he joined the WHO. Prof. Lambo set an enviable record in his chosen career and pulled a long chain of awards and honours. Founder of the Association of Psychiatrists in Africa, Prof. Lambo was a colossus who bestrode the medical field and left his footprints in the sand of time. In the field of mental health, he identified and established cultural factors in psychiatric disorders and established a methodology of diagnosis and cure, which many practitioners in the world have adopted. The Aro Psychiatric hospital which he established has remained till today one of the best in terms of both facilities and prophylaxis on the continent of Africa. Some of the projects and programmes initiated by him at WHO are today points of reference in the medical profession. As the founder of the Lambo Foundation he made good his promise to improve the standard of medical practice by providing equipment and facilities for Universities and particularly through his contribution to medical research. In this paper, attempt is made at examining the contribution of Prof. Lambo to the general health care delivery system. Specifically, the work examines Lambo’s role as a pioneer mental health Physician. The work also evaluates the impact of Prof. Lambo on the medical profession. It is hoped that a study of Lambo’s career would help us to appreciate how much effort is being expended by some committed Africans in combating illnesses and improving the general health care delivery amongst African people. It will also contribute to general knowledge on individual actors that have helped to shape the course of human history.