South Africa has become an international focal point around AIDS, both as a location of scandal due to President Mbeki's controversial denial in 2000 that HIV causes AIDS and as center of a transnational AIDS treatment access movement. The catalyst for this movement has been the Treatment Action Campaign (TAC), a grassroots organization recently nominated for a Nobel Prize. In this paper, based on 16 months of ethnographic participatory research with TAC, I examine TAC as a national and transnational force. In particular, I analyze the way TAC has borrowed anti-apartheid freedom songs and cultural forms, such as toyi toying, political funerals, and defiance campaigns and employed them against the ANC government in this new struggle for social justice, known in South Africa and elsewhere as the "new apartheid." Secondly, I borrow Brecher, et al.'s (2000) notion of "globalization from below" to theorize TAC's international victories against the pharmaceutical industry and its relationships, frequently cyber in nature, to other AIDS treatment access organizations to argue for the radical potential of frequently destructive transnational flows of capital.